We Love It's Guide to…

SIDE EFFECTS

A twisted trial of pill roulette for up to 4 players (solo or online). Pick your poison. Use experimental items to shift the odds. And remember: only one of you can survive.

85%
of 890 reviews
$4.99
Released: Nov 21, 2025  •  Developers: hirohun…  •  Publisher: Free Lives

The Developer Says...

Up to four test subjects. One twisted medical trial. Only one leaves.

Welcome to Side Effects: a tense, turn-based medical roulette game. Each round you'll be presented with a selection of pills. Some are helpful, some are harmful, and some mean instant death. You never know what you're about to consume or what it might do to your mind or body. Winning means outlasting – AKA, outliving – your opponent across the table.

Resist

Every pill impacts your resistance. Manage it wisely: zero resistance means death.

Experiment

Between rounds, you can choose from a range of experimental items and treatments that can shift the odds in your favor, from vaccines to mouth clamps.

You’re not alone

The other patient wants to outlast you. They’ll bluff, adapt, and use everything at their disposal to keep breathing one dose longer than you.

Would you like to participate?

This trial includes:

  • A single player mode

  • A multiplayer mode (2-4 Players)

  • 15+ unique items 

  • 6 pill types to test

Back of the Box Details

Steam Deck

Verified

DLC

None

DRM/EULA Notices

None

Achievements

None

Ratings

None

Demo

None

Metacritic

None

Content Notices

In-game chat, Online interactivity

Controller Support

None

Reviews

85%

Very Positive

Based on 890 reviews


Individual reviews are not available yet.