Games Like Genome Guardian

Genome Guardian

COMBINE WEAPONS in the microscopic roguelite turret shooter with macroscopic depth. Survive 6 modes using an astounding array of turrets, perks, mutations and power-ups on this psychedelic journey to the heart of the abyss. Shmup Mode turns it into a vertical shoot 'em up!

★ ROCKET RATS ★ PENGPONG ★ ECHOES OF RED ★ BROTANK ★ STARFORGED LEGACY ★ ARMY OF RUIN ★ BLAZING BEAKS ★ SUBLEVEL ZERO REDUX ★ VOID BASTARDS ★ THEY ARE COMING ★ RABBIT HOLE ★ EMPTY SHELL ★ WE ♥ IT 
1

Rocket Rats

94% 👍 OF 2.7K
About This Game

Rocket Rats is a survivors-like game where you defeat cheese-based astral bodies in space – as a rat! Clear waves of enemies, collect cheese, upgrade your gear, and conquer the moon!

Player reviews say you can…

  • …pull a late upgrade that makes every temporary bonus you earned become permanent all at once.
  • …get so overpowered that you can stop moving entirely and just keep picking cards while enemies die around you.
  • …turn maxed-out upgrade pairs into rare combo evolutions, like poison arrows or stars that summon lightning.
7

Blazing Beaks

83% 👍 OF 2.6K
About This Game

Roguelite - where too much greediness can be fatal. A colorful world with armed birds blazing their way through piles of mutants, monsters and creepy creatures. Lots of mysteries to unravel, secrets to discover and levels to explore.

Player reviews say you can…

  • …Carry Cursed Artifacts
  • …Trade Curses for Loot
  • …Team Up in Story Mode
8

Sublevel Zero Redux

87% 👍 OF 529
About This Game

Sublevel Zero Redux is a roguelite six-degree-of-freedom shooter in a universe where reality is falling apart. Use your zero-g gunship to fight through a vast underground facility, looting advanced weapons to destroy hordes of deadly enemies.

Player reviews say you can…

  • …Fly in Every Direction
  • …Fight in Zero Gravity
  • …Scavenge Random Weapons
9

Void Bastards

86% 👍 OF 5.4K
About This Game

Inspired by BioShock and System Shock 2, Void Bastards is a revolutionary new strategy-shooter that will test your wits as well as exercise your aim. Can you lead the misfit prisoners of the Void Ark through the derelict spaceships and myriad dangers of the Sargasso Nebula?

Player reviews say you can…

  • …Plan Ship Raids
  • …Loot Derelict Ships
  • …Manipulate Ship Systems
10

They Are Coming

91% 👍 OF 646
About This Game

They Are Coming is a hybrid game that combines roguelike, tower defense, and base building in a side-scrolling shooter format. It offers a straightforward gaming experience for pure enjoyment.

Player reviews say you can…

  • …Defend the Orphanage
  • …Build Zombie Barriers
  • …Fight With Guns and Melee
11

Rabbit Hole

90% 👍 OF 1.7K
About This Game

Rabbit Hole is a fast paced, tough-as-nails 2D RogueLike-Shooter, made with love for the genre. You are Disc, someone who was suddenly brought to the Rabbit Hole. Collect guns, fight foes and meet strange new characters on your descent to the bottom, all in an attempt to find your heart again.

Player reviews say you can…

  • …Battle Through Rooms
  • …Dodge Boss Attacks
  • …Collect 50+ Guns
12

EMPTY SHELL

88% 👍 OF 862
About This Game

EMPTY SHELL will throw you in a dark industrial environment, a secret facility on a Japanese island. Each volunteer has signed a contract for a "recovery operation" without being privy to too many details. A tense roguelite survival horror with a top down perspective.

Player reviews say you can…

  • …Navigate Shifting Facility Levels
  • …Return as New Volunteers
  • …Recover Fallen Gear