Games Like Defend Your Life: TD

Defend Your Life: TD

Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria. Levels and units correspond to reality of human anatomy.

★ DEAR MAGICAL GIRLS ★ CREEPER WORLD: ANNIVERSARY EDITION ★ CREEPER WORLD 3: ARC ETERNAL ★ ZOMBO BUSTER ADVANCE ★ CURSED TREASURE 2 ★ CREEPER WORLD 2: ANNIVERSARY EDITION ★ KINGDOM RUSH VENGEANCE - TOWER DEFENSE ★ BLOONS MONKEY CITY ★ DEATHTRAP ★ X-MORPH: DEFENSE ★ KUNITSU-GAMI: PATH OF THE GODDESS ★ ORCS MUST DIE! ★ WE ♥ IT 
1

Dear Magical Girls

97% 👍 OF 292
About This Game

Dear Magical Girls is a story-driven defense game about an overworked magical girl protecting the Mana Stone that keeps the city running. Move the vertices to reshape your magical field. Unlock modules and enchants, and build your own strategy to survive against waves of monsters.

REL Jul 31, 2026 FREE ON STEAM See This Game →
2

Creeper World: Anniversary Edition

97% 👍 OF 983
About This Game

Imagine an enemy that is everywhere and moves like a giant, organic mass across the map. Imagine your base and your people surrounded by a blanket of crushing destruction from all directions. Your only hope, well what hope? Then you take the high ground and pound this enemy into oblivion.

Player reviews say you can…

  • …Hold Back the Creeper
  • …Build Energy Networks
  • …Push Across the Map
3

Creeper World 3: Arc Eternal

96% 👍 OF 4.8K
About This Game

Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

Player reviews say you can…

  • …Outbuild the Creeper
  • …Link Guns to Power
  • …Reshape the Terrain
5

Cursed Treasure 2

82% 👍 OF 588
About This Game

Why be good when you can be... bad? Cursed Treasure 2 is an addictive tower-defense game that puts the power of darkness at your fingertips. Build towers of powerful orcs, demons, and undead, and master powerful spells, to protect your precious hoard from all manner of no-good do-gooders.

Player reviews say you can…

  • …Defend Your Gems
  • …Build Three Faction Towers
  • …Drop Meteors on Heroes
6

Creeper World 2: Anniversary Edition

90% 👍 OF 506
About This Game

Deceptively simple... amazingly deep. Creeper World 2 thrusts you into the 14th millennium fighting and enemy that flows and oozes through the terrain. Employ advanced weapons,gravity manipulating repulsors, wormhole like rifts, and your own wit against this never yielding enemy.

Player reviews say you can…

  • …Dig Through Terrain
  • …Shape Creeper Chokepoints
  • …Push Back Flowing Creeper
7

Kingdom Rush Vengeance - Tower Defense

94% 👍 OF 10K
About This Game

It's payback time! Lead your mighty dark army and make the Kingdom tremble with every step. Build powerful towers, choose your arsenal for destruction, and find the deadliest combination - train legendary heroes and lead them to victory!

Player reviews say you can…

  • …pick 5 towers per mission from a pool of up to 18.
  • …use a hero ability even while your hero is dead.
  • …play the campaign as the villain, reclaiming the kingdom from the heroes who used to stop you.
8

Bloons Monkey City

91% 👍 OF 6.8K
About This Game

Create, upgrade, and customize your very own Bloons Monkey City in this groundbreaking blend of city building and tower defense awesomeness!

Player reviews say you can…

  • …Capture Bloon Territory
  • …Build Monkey City
  • …Unlock Monkey Towers
REL Apr 10, 2020 FREE ON STEAM See This Game →
9

Deathtrap

84% 👍 OF 2.3K
About This Game

Deathtrap is a Tower Defense game with strong action-RPG elements, a game of vicious tricks, killing machines, rotating blades and splattering blood.

Player reviews say you can…

  • …Fight Beside Your Traps
  • …Build Trap Combinations
  • …Control Invading Monsters
10

X-Morph: Defense

91% 👍 OF 4.2K
About This Game

Unique fusion of a top-down shooter and tower defense strategy. You are the invader! Use destructive weapons or lead your enemies into a maze of towers. Strategize in the build mode by carefully selecting various types of alien towers or throw yourself right into the heat of the battle.

Player reviews say you can…

  • …Build Enemy Mazes
  • …Reshape Routes with Destruction
  • …Fly an Alien Fighter
11

Kunitsu-Gami: Path of the Goddess

92% 👍 OF 2.6K
About This Game

A new tale of the Kami awaits... Kunitsu-Gami: Path of the Goddess is a unique Japanese-inspired, single player Kagura Action Strategy game.

Player reviews say you can…

  • …Defend Through Night
  • …Assign Villager Roles
  • …Fight Beside Your Units
12

Orcs Must Die!

96% 👍 OF 8.5K
About This Game

Slice them, burn them, skewer them, and launch them - no matter how you get it done, orcs must die in this fantasy action-strategy game from Robot Entertainment.

Player reviews say you can…

  • …Build Trap Corridors
  • …Redirect Orc Waves
  • …Fight Alongside Traps